Research Paper
Assessment of Selenium, Copper and Zinc in Hypothyroid cases
Author: Dr Ragini Srivastava,, Dr Akash Bansal,, Dr Antara Kashyap, Dr Rajeev Lohokare
Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi.
email- ragsriv@gmail.com
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Abstract : Hypothyroidism is a condition characterized by abnormally low thyroid hormone production. Because thyroid hormone affects growth, development, and many cellular processes inadequate thyroid hormone has widespread consequences for the body.
Hypothyroidism is more
common than reported. It is an endemic disease in the northern part of our country. The causes for
hypothyroidism in this region are not very clear. Therefore, the role of trace elements in hypothyroidism
has been taken up in this study to find if there is any association or not.
Methods:
This prospective randomized study consisted of 50 cases in the hypothyroid group that was matched with 26 controls in normal thyroid group. Biochemical parameters such Thyroid Stimulating Hormone, Levothyroxine, Liothyronine, Protein, albumin, globulin, Copper, Zinc, Selenium and Alkaline Phosphatase were determined.
Results:
The range level of Copper and selenium was found to be similar and within normal limits among cases and controls of this region. The level of Zinc was lower in cases as compare to controls in females of less than 50 years age group of this region. The levels of total serum Alkaline phosphatase , total protein, albumin and globulin and A/G ratio were within the normal limits among cases and controls of this geographical region.
